Tag Archives: Schizophrenia

Childhood infections: Early fright and long-term hazard

Children get sick. A lot. Part of the reason children seemingly catch everything around us that’s bad is that their immune systems need to grow up, too. The immune system has to learn how to deal with the dangerous world around us with the difference being that it doesn’t care about cars or bullies getting in its way but instead about tiny pathogens like viruses and bacteria who can wrack havoc in our bodies. When immune systems grow up they invariably make mistakes or get taken by surprise on their way. Once this happens, not only do kids’ reddened little cheeks and large, watery eyes cause parents to do everything in their power to help, but infections in childhood can sometimes pose a real threat with children requiring hospitalisation and medical care. More often than not, this is just an early fright and no need for future bother once the acute infection is defeated. As it turns out, however, infections might pose long-term risks, too. Resulting from a collaboration between University of Cambridge and Karolinska Institutet, we just published a study in the journal JAMA Psychiatry, which shows that childhood infections might increase our risk for later development of severe mental illnesses such as schizophrenia. Strangely enough, the reason for infection posing such risk might be partly related to another risk factor for schizophrenia: low intelligence.

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Hallucinations: It’s not what you hear but expect to hear

Hallucinations are a cue word for schizophrenia and severe mental illness. Yet, in themselves, hallucinations are neither unique to schizophrenia, nor are they uniquely related to ill people. Instead, they are common in other diseases, such as Parkinson’s, and even occur in some people without any mental illnesses. Have you ever heard your name in a place where you knew nobody could have said it? Have you ever had a creepy-crawly feeling without anything bugging you? Or have you ever thought you’ve seen someone you know at first glance, yet realised later it was someone else? Chances are high that you’ve had one of these experiences because hallucinations lie on a spectrum. On one end of the spectrum, people suffering from severe diseases like schizophrenia might hear vicious voices they can’t turn off, that are terrifying and aggressive, while, on the other end, there may be such common everyday misperceptions. In fact, if you regarded my very minor examples as hallucinations, we all might be susceptible to hallucinating to an extent and a recent study published in the renowned journal Science does indeed suggest that this is the case. The study led by researchers Powers, Mathys, and Corlett has looked closely at how hallucinations come to life and suggests they may be failures in how we integrate our previous knowledge with the actual perceptual input.

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